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ea0014p248 | (1) | ECE2007

Neuroendocrine and genetic aspects of metabolic disturbances in women with simple obesity, polycystic ovary syndrome (PCOS) and eating disorders

Baranowska-Bik Agnieszka , Bik Wojciech , Wolinska-Witort Ewa , Gaj Pawel , Mikula Michal , Bragoszewski Piotr , Ostrowski Jerzy , Baranowska Boguslawa

Neuropeptides and adipocytokines influence metabolic homeostasis and food intake. Deregulation in their secretion leads to insulin resistance or metabolic syndrome. Adiponectin possesses anti-diabetic and insulin sensitizing properties. Expression of this gene remains under control of nuclear peroxisome proliferator-activated receptor (PPAR)-gamma. Ghrelin, an endogenous ligand for GH secratagogue receptor (GHSR), modulates metabolic homeostasis. A high amino-acid homology and...

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Neuroendocrine and genetic aspects of metabolic disturbances in women with simple obesity, polycystic ovary syndrome (PCOS) and eating disorders

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